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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTPN14 All Species: 35.76
Human Site: Y1170 Identified Species: 78.67
UniProt: Q15678 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15678 NP_005392.2 1187 135261 Y1170 M I Q T I A Q Y K F V Y Q V L
Chimpanzee Pan troglodytes XP_001171329 1187 135241 Y1170 M I Q T I A Q Y K F V Y Q V L
Rhesus Macaque Macaca mulatta XP_001106167 1187 135194 Y1170 M I Q T I A Q Y K F V Y Q V L
Dog Lupus familis XP_849236 1187 134903 Y1170 M I Q T I T Q Y K F V Y Q V L
Cat Felis silvestris
Mouse Mus musculus Q62130 1189 135012 Y1172 M I Q T I A Q Y K F V Y Q V L
Rat Rattus norvegicus Q62728 1175 133393 Y1158 L V Q T L S Q Y T F V Y R V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511302 1193 135259 Y1176 M I Q T I A Q Y K F V Y Q V L
Chicken Gallus gallus XP_419419 1191 135566 Y1174 M I Q T I A Q Y K F V Y Q V L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001339962 834 94004 T818 V Q T L S Q Y T F I Y K V L I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P28191 1026 115075 R1010 F V C E S I L R A Y H D G T I
Sea Urchin Strong. purpuratus XP_796215 1318 147575 Y1301 M V Q T V G Q Y T F V Y K A L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.9 95.6 N.A. 91.5 53.7 N.A. 87.9 84.9 N.A. 32.8 N.A. N.A. N.A. 24.7 34.5
Protein Similarity: 100 99.7 99.5 97.2 N.A. 95.6 70.7 N.A. 92.1 91.5 N.A. 48.1 N.A. N.A. N.A. 42 51.7
P-Site Identity: 100 100 100 93.3 N.A. 100 60 N.A. 100 100 N.A. 0 N.A. N.A. N.A. 0 60
P-Site Similarity: 100 100 100 93.3 N.A. 100 93.3 N.A. 100 100 N.A. 20 N.A. N.A. N.A. 20 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 55 0 0 10 0 0 0 0 10 0 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 10 0 0 0 0 0 0 0 10 82 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 64 0 0 64 10 0 0 0 10 0 0 0 0 19 % I
% Lys: 0 0 0 0 0 0 0 0 64 0 0 10 10 0 0 % K
% Leu: 10 0 0 10 10 0 10 0 0 0 0 0 0 10 82 % L
% Met: 73 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 82 0 0 10 82 0 0 0 0 0 64 0 0 % Q
% Arg: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % R
% Ser: 0 0 0 0 19 10 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 10 82 0 10 0 10 19 0 0 0 0 10 0 % T
% Val: 10 28 0 0 10 0 0 0 0 0 82 0 10 73 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 82 0 10 10 82 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _